Introduction to Drugs for Hypercholesterol

facial expression do of cholestyramine embroil the fol minoring: tumors (found in animals only); black stools, weight dismissal, put up pain, nausea, and vomiting, (r atomic number 18); and constipation, upset prevail (common). Side effects of colestipol allow: black stools, weight loss, bide pain, nausea, and vomiting, (rare); and constipation, indigestion (common) (Micromedex, 2000).

Niacin lowers cholesterol and fat levels in the blood. The mutual precautions taken for drug use (medical conditions) are applicable for nicotinic acid usage. Side effects include dark urine, gray stools, loss of appetite, yellow eyes or skin, stomach pain, flushing, and headache; these effects are not common and tend to occur with drawn-out use of extended-release niacin. High doses can result in fever, faintness, patronage urination and thirst, dry and itching skin, egotistic legs and feet, joint, back, or stomach pain, flunk and irregular, slow, or fast heartbeat (Micromedex, 2000).

The HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitors, Atorvastatin, Cerivastatin, Fluvastatin, Lovastatin, Pravastatin, and Simvastatin are used to lower cholesterol and fat levels in the blood. aesculapian precautions are taken forrader using these prescription drugs. Side effects of these medicines include the following: fever, muscle and stomach pain, weakness (common or rare); dizziness, headache, constipation or diarrhea, gas, nausea or stomach pain, rash (common); and decrea

In conclusion, it appears that either of the above mentioned drugs fuddle been found to be effective agents for the drop-off of hypercholesterol. perfumes of each must be considered, however, since in almost cases, they may outweigh their benefits.

Guyton, J. R., Blazing, M. A., Hagar, J., Kashyap, M. L., Knopp, R. H., McKenney, J. M., Nash, D. T., & Nash, S. D. (2000). Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group. Archives internal Medicine, 24(8), 1177-1184.

Brown, B. G., Bardsley, J., Poulin, D., Hillger, L. A., Dowdy, A., Maher, V. M., Zhao, X. Q., Albers, J. J., & Knopp, R. H. (1997).

Moderate dose, three-drug therapy with niacin, lovastatin, and colestipol to reduce oddment lipoprotein cholesterol <100 mb> Probucol lowers cholesterol levels in the blood. Medical conditions are considered before using this drug. Side effects include the following: swollen face, hands, feet or mouth, bleeding or bruising, and tiredness (rare); and fast or irregular heartbeat, dizziness or fainting, headache, numbness or chill of face, fingers, or toes, bloating, diarrhea, stomach pain with nausea and vomiting (common) (Micromedex, 2000).

Okubo, M., Nakamura, M., Horii, A., Kamata, K., Takeuchi, Y., Tsukamoto, Y., Kobayashi, N., Sato, K., & Endo, T. (1999). Effect of probucol on hypersholesterolemia in renal transplant patients. Kidney International Suppl., 71(S), S229-S230.

clofibrate lowers cholesterol and triglyceride levels in the blood. As with gemfibrozil, this drug may have unwanted side effects. Clofibrate may result in the addd risk of cancer, liver disease, pancreatitis, and gallstones. Additional medical problems would increase concern for drug usage. Other side effects include: irregular heartbeat, chest pain, short breath, cough, hoarseness, stomach pain or indigest
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